منابع مشابه
Protease Inhibitors as Ad-hoc Antibiotics
Received: December 08, 2015 Revised: April 26, 2016 Accepted: April 27, 2016 Abstract: Background: Proteases are important enzymes that can degrade proteins and are found in animals, plants, bacteria, fungi and viruses. The action of proteases can be controlled by Protease Inhibitors (PIs), chemical or proteinaceous in nature that can block the active site of protease. Since the step catalyzed ...
متن کاملOne-pot Synthesis of Amidoalkyl Naphthol Derivatives as Potential Nucleoside Antibiotics and HIV Protease Inhibitors using Nano-SnO2 as an Efficient Catalyst
An efficient three-component one-pot synthesis of 1-amidoalkyl-2-naphthols from 2-naphthol, aldehydes, and acetamide using nano-SnO2as catalyst is described. The reactions were carried out at 80oC under water-solvent media. The structures of the compounds were characterized by IR, 1HNMR, 13C-NMR, and Mass spectra and by elemental analysis. The advantages of the effective meth...
متن کاملProtease inhibitors as antiviral agents.
Currently, there are a number of approved antiviral agents for use in the treatment of viral infections. However, many instances exist in which the use of a second antiviral agent would be beneficial because it would allow the option of either an alternative or a combination therapeutic approach. Accordingly, virus-encoded proteases have emerged as new targets for antiviral intervention. Molecu...
متن کاملImproving Vehicular Ad-Hoc Network Stability Using Meta-Heuristic Algorithms
Vehicular ad-hoc network (VANET) is an important component of intelligent transportation systems, in which vehicles are equipped with on-board computing and communication devices which enable vehicle-to-vehicle communication. Consequently, with regard to larger communication due to the greater number of vehicles, stability of connectivity would be a challenging problem. Clustering technique as ...
متن کاملA Fuzzy Realistic Mobility Model for Ad hoc Networks
Realistic mobility models can demonstrate more precise evaluation results because their parameters are closer to the reality. In this paper a realistic Fuzzy Mobility Model has been proposed. This model has rules which are changeable depending on nodes and environmental conditions. It seems that this model is more complete than other mobility models.After simulation, it was found out that not o...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Open Pharmaceutical Sciences Journal
سال: 2016
ISSN: 1874-8449
DOI: 10.2174/1874844901603010131